Pentapeptide-18 Leuphasyl peptide bulk powder for expression line cosmetic formulations. High purity OEM supplier for anti-aging skincare.
What is Pentapeptide-18？
Pentapeptide-18 powder is a high-performance cosmetic peptide designed to reduce the appearance of fine lines and expression wrinkles, particularly in areas such as the forehead and around the eyes.
It works by supporting a relaxation mechanism in facial muscle micro-contractions, helping to smooth skin texture and improve visible signs of aging without invasive procedures.
We ingredient is widely used in anti-aging serums, eye creams, and high-end skincare formulations due to its excellent compatibility and stability in cosmetic systems.
Pentapeptide-18 Powder Specifications
| Item |
Standard |
| Product Name |
Pentapeptide-18 Powder |
| INCI Name |
Pentapeptide-18 |
| Appearance |
White to off-white lyophilized powder |
| Purity (HPLC) |
≥ 98% |
| Molecular Formula |
C34H60N12O12 |
| Molecular Weight |
~800 Da |
| Solubility |
Soluble in water |
| Application Range |
100–1000 ppm in formulations |
| Storage Temperature |
2–8°C (recommended) |
| Shelf Life |
24 months (sealed, dry condition) |
Wholesale Pentapeptide-18 Powder (Leuphasyl) | High Purity Cosmetic Neuro-Peptide Raw Material for Anti-Wrinkle Skincare Formulations | Manufacturer Supply
Manufacturing Process
Solid-Phase Peptide Synthesis (SPPS) using Fmoc-protected amino acids
Stepwise peptide chain assembly under controlled reaction conditions
Cleavage from resin and side-chain deprotection
Crude peptide filtration and precipitation
High-performance purification via preparative HPLC
Freeze-drying (lyophilization) into powder form
Sterile filtration and final quality testing (HPLC, MS, microbial limits)
Pentapeptide-18 Powder to Cosmetic & Personal Care Solutions
Anti-Wrinkle Face Serum (Water-Based Active Serum)
| Ingredient |
Function |
% |
| Purified Water |
Solvent |
q.s. to 100 |
| Glycerin |
Humectant |
3.0 – 5.0% |
| Hyaluronic Acid |
Hydration booster |
0.1 – 0.3% |
| Pentapeptide-18 |
Anti-wrinkle active |
0.01 – 0.05% |
| Acetyl Hexapeptide-8 |
Synergistic peptide |
0.02 – 0.10% |
| Panthenol |
Skin soothing |
1.0 – 2.0% |
| Carbomer |
Thickener |
0.2 – 0.5% |
| Preservative |
Protection system |
0.8 – 1.0% |
| Triethanolamine |
pH adjuster |
q.s. |
Anti-Aging Eye Cream Formula
| Ingredient |
Function |
% |
| Deionized Water |
Base |
q.s. |
| Caprylic/Capric Triglyceride |
Emollient |
4.0 – 8.0% |
| Shea Butter |
Nourishment |
2.0 – 5.0% |
| Pentapeptide-18 |
Anti-wrinkle peptide |
0.01 – 0.03% |
| Niacinamide |
Brightening |
2.0 – 4.0% |
| Ceramide Complex |
Barrier repair |
0.5 – 1.0% |
| Emulsifier (Olivem 1000) |
Stability |
3.0 – 5.0% |
| Preservative |
Safety |
0.8 – 1.0% |
High-End Anti-Aging Ampoule
| Ingredient |
Function |
Range |
| Water (Aqua) |
Carrier |
q.s. |
| Pentapeptide-18 |
Core active |
0.02 – 0.05% |
| Sodium Hyaluronate |
Hydration |
0.2 – 0.5% |
| Acetyl Octapeptide-3 |
Expression line reduction |
0.02 – 0.05% |
| Beta-Glucan |
Repair & soothing |
0.5 – 1.0% |
| Allantoin |
Skin calming |
0.2 – 0.5% |
Pentapeptide-18 of Recommended Dosage
| Product Type |
Recommended |
| Serums |
0.01% – 0.05% |
| Eye Creams |
0.01% – 0.03% |
| Ampoules |
0.02% – 0.05% |
| Luxury Skincare Lines |
Up to 0.05% |
| Combined peptide systems |
0.01% – 0.10% total peptide blend |
*Tip: Add Pentapeptide-18 during the cool-down phase (<40°C) to maintain bioactivity.
Contact Us for Wholesale Orders
Bulk Pentapeptide-18 Powder Price from Peptidchem, is a cosmetic peptides manufacturer with more than 20 years of experience. We have our own laboratories and warehouses in the United States. The company has obtained multiple certifications including ISO9001, FDA, HALAL, KOSHER, FSSC22000, and thirteen patent certifications. Contact us now!
FAQs:
Q1.Is Pentapeptide-18 safe for skin application?
Yes. It is widely used in cosmetic-grade formulations and is considered safe when used within recommended concentrations.
Q2.Can Pentapeptide-18 be combined with other peptides?
Yes, it is highly compatible with other peptides such as Acetyl Hexapeptide-8 and Matrixyl.
Q3.What is the recommended storage condition?
Store in a cool, dry environment at 2–8°C, away from light and moisture.
Q4.What is your minimum order quantity (MOQ)?
MOQ varies depending on customization, typically starting from 1g–10g for samples and 25kg+ for bulk orders.
References
INCI Cosmetic Ingredient Database (Pentapeptide-18 listing)
General peptide synthesis and cosmetic formulation literature
Supplier-grade peptide manufacturing standards (SPPS + HPLC purification practices)
