As a professional cosmetic peptide manufacturer, we provide high-purity palmitoyl pentapeptide-4 powder produced under strict quality control standards for global cosmetic brands, contract manufacturers, laboratories, and distributors.
What is Palmitoyl Pentapeptide-4 Powder?
At cosmetic peptide raw material manufacturer, Palmitoyl pentapeptide-4 powder is a synthetic signal peptide widely used in advanced anti-aging skincare formulations. It is designed to help support collagen production and improve the appearance of fine lines and wrinkles. Due to its excellent skin compatibility and stability, it has become one of the most recognized cosmetic peptides used in premium facial serums, anti-aging creams, eye treatments, and regenerative skincare products.
Palmitoyl Pentapeptide-4 Powder Source
Palmitoyl Pentapeptide-4 is synthesized through a process called solid-phase peptide synthesis (SPPS). In this process, amino acids are sequentially added to form a specific peptide chain (the pentapeptide), which consists of five amino acids. After the peptide chain is formed, it is linked to palmitic acid, a fatty acid, to enhance its skin penetration. The final compound is then purified and tested for quality.
Palmitoyl Pentapeptide-4 Powder Specification
| Item | Specification |
| Product Name | Palmitoyl Pentapeptide-4 |
| INCI Name | Matrixyl |
| CAS Number | 214047-00-4 |
| Molecular Formula | C39H75N7O10 |
| Molecular Weight | 802.05 g/mol |
| Appearance | White to Off-White Powder |
| Purity | ≥98% |
| Test Method | HPLC |
| Solubility | Soluble in Water and Cosmetic Solvents |
| Application | Anti-Aging Cosmetics |
| Grade | Cosmetic Grade |
| Shelf Life | 24 Months |
Manufacturing Process of Palmitoyl Pentapeptide-4 Powder
Peptidchem Palmitoyl Pentapeptide-4 Powder is manufactured using advanced Solid-Phase Peptide Synthesis (SPPS) technology.
Manufacturing Steps:
1.Raw Material Selection
2.Solid-Phase Peptide Synthesis
3.Palmitic Acid Coupling
4.Cleavage and Deprotection
5.Purification by Preparative HPLC
6.Concentration
7.Lyophilization (Freeze Drying)
8.Quality Control Testing
9.Packaging
10.Export Shipment
We process ensures high purity, batch consistency, and excellent product stability.
Palmitoyl Pentapeptide-4 Powder to Cosmetic & Personal Care Solution
1.Anti-Aging Cosmetic Essence (Serum)
| Ingredient | INCI | % |
| Deionized Water | Aqua | qs to 100 |
| Glycerin | Glycerin | 5 |
| Butylene Glycol | Butylene Glycol | 6 |
| Betaine | Betaine | 2 |
| Sodium Hyaluronate | Sodium Hyaluronate | 0.2 |
| Niacinamide | Niacinamide | 3 |
| Panthenol | Panthenol | 1 |
| Palmitoyl Pentapeptide-4 | Active Ingredient | 0.005 |
| Acetyl Hexapeptide-8 | Active Ingredient | 0.005 |
| Ectoin | Ectoin | 0.3 |
| Hydroxyacetophenone | Antioxidant | 0.3 |
| Preservative | Cosmetic Grade | 0.8 |
| Fragrance | Optional | 0.1 |
Recommended pH: 5.5–6.0
2.Anti-Aging Firming Cream
| Ingredient | % |
| Purified Water | qs |
| Glycerin | 4 |
| Caprylic/Capric Triglyceride | 8 |
| Shea Butter | 4 |
| Squalane | 3 |
| Cetearyl Alcohol | 3 |
| Glyceryl Stearate | 2.5 |
| Ceramide NP | 0.3 |
| Sodium Hyaluronate | 0.15 |
| Niacinamide | 2 |
| Palmitoyl Pentapeptide-4 | 0.008 |
| Palmitoyl Tripeptide-1 | 0.005 |
| Palmitoyl Tetrapeptide-7 | 0.005 |
| Tocopherol | 0.5 |
| Preservative | 0.8 |
Recommended pH: 5.2–5.8
3.Anti-Aging Facial Mask Essence
| Ingredient | % |
| Purified Water | qs |
| Glycerin | 5 |
| Propanediol | 4 |
| Betaine | 2 |
| Sodium Hyaluronate | 0.15 |
| Tremella Extract | 1 |
| Panthenol | 1 |
| Allantoin | 0.3 |
| Palmitoyl Pentapeptide-4 | 0.005 |
| Copper Peptide | 0.002 |
| Ectoin | 0.3 |
| Preservative | 0.8 |
4.Anti-Aging Eye Cream
| Ingredient | % |
| Purified Water | qs |
| Glycerin | 5 |
| Squalane | 5 |
| Jojoba Oil | 3 |
| Caprylic/Capric Triglyceride | 4 |
| Cetearyl Alcohol | 2 |
| Ceramide NP | 0.3 |
| Sodium Hyaluronate | 0.1 |
| Caffeine | 1 |
| Panthenol | 1 |
| Palmitoyl Pentapeptide-4 | 0.005 |
| Acetyl Tetrapeptide-5 | 0.003 |
| Vitamin E | 0.5 |
| Preservative | 0.8 |
Recommended pH: 5.5–6.0
Recommended Ingredient Combinations
| Ingredient | Compatibility | Function |
| Sodium Hyaluronate | ★★★★★ | Hydration |
| Niacinamide | ★★★★★ | Brightening & barrier support |
| Ectoin | ★★★★★ | Skin protection |
| Ceramide NP | ★★★★★ | Barrier repair |
| Panthenol | ★★★★★ | Soothing |
| Acetyl Hexapeptide-8 | ★★★★★ | Expression line care |
| Copper Tripeptide-1 | ★★★★★ | Premium peptide complex |
| Palmitoyl Tripeptide-1 | ★★★★★ | Firming support |
| Palmitoyl Tetrapeptide-7 | ★★★★★ | Anti-aging peptide synergy |
| Squalane | ★★★★★ | Moisturizing |
| Tocopherol | ★★★★★ | Antioxidant support |
Why Choose Peptidchem?
Bulk Palmitoyl Pentapeptide-4 Powder, is a supplement and peptide manufacturer with more than 20 years of experience. We have our own laboratories and warehouses in the United States. The company has obtained multiple certifications including ISO9001, FDA, HALAL, KOSHER, FSSC22000, and thirteen patent certifications. Contact us now!
Cosmetic Peptide Manufacturer FAQs:
Q1:Is Palmitoyl Pentapeptide-4 suitable for serums?
Yes. It is one of the most popular active ingredients used in anti-aging facial serums and peptide concentrates.
Q2:What is the recommended formulation dosage?
Most formulations use between 0.001% and 0.02%, depending on product type and formulation objectives.
Q3:Can it be combined with hyaluronic acid?
Yes. Palmitoyl Pentapeptide-4 is commonly formulated with hyaluronic acid, niacinamide, ceramides, and other cosmetic peptides.
Q4:Is the product cosmetic grade?
Yes. we Palmitoyl Pentapeptide-4 Powder is manufactured specifically for cosmetic and personal care applications.
Q5:What documents are available?
We can provide COA, MSDS, TDS, specification sheets, and other export-related documentation upon request.
References
International Cosmetic Ingredient Dictionary (INCI).
Cosmetic Ingredient Review (CIR) Safety Assessment Reports.
Journal of Cosmetic Dermatology.
International Journal of Cosmetic Science.
Personal Care Products Council (PCPC).
Cosmetic peptide formulation literature and peptide synthesis references.
