Top suppliers of bulk Berberine HCl Powder include peptidchem.com for to-mid-size bulk quantities (ranging from grams to kilograms) and industrial providers like BulkSupplements, PureBulk or wholesale distributors like Ingredients Online for large-scale commercial and manufacturing needs.
What is Source of Berberine HCl Powder?
Pure Berberine Hydrochloride is a purified alkaloid compound derived from berberine-rich plants, including Berberis species (Barberry), Coptis chinensis (Chinese Goldthread), Phellodendron, and Hydrastis canadensis (Goldenseal). The raw botanical materials are extracted, purified, and converted into the hydrochloride salt form to improve stability and processing characteristics.
Berberine HCl is widely used as a premium active ingredient in dietary supplements, functional foods, and nutraceutical formulations.
Berberine HCl Powder Specifications
| Test Item | Specification |
|---|---|
| Product Name | Berberine Hydrochloride Powder |
| Appearance | Yellow crystalline powder |
| Active Ingredient | Berberine HCl |
| Purity | ≥98% |
| CAS Number | 633-65-8 |
| Molecular Formula | C20H18ClNO4 |
| Molecular Weight | 371.82 g/mol |
| Identification | Positive |
| Particle Size | 80 mesh / 100 mesh |
| Loss on Drying | ≤5.0% |
| Ash Content | ≤1.0% |
| Heavy Metals | ≤10 ppm |
| Lead (Pb) | ≤3 ppm |
| Arsenic (As) | ≤2 ppm |
| Cadmium (Cd) | ≤1 ppm |
| Mercury (Hg) | ≤0.1 ppm |
| Total Plate Count | ≤1,000 CFU/g |
| Yeast & Mold | ≤100 CFU/g |
| E. coli | Negative |
| Salmonella | Negative |
| Solvent Residue | Meet USP requirements |
| Storage | Cool, dry, dark place |
| Shelf Life | 24 months |
Berberine HCl Powder of Manufacturing Process
Our Berberine HCl Powder manufacturing process follows controlled extraction and purification procedures:
1. Raw Material Selection
High-quality berberine-containing botanical materials are selected and tested for:
- Botanical identity
- Heavy metals
- Pesticides
- Microbial contamination
- Active compound content
2. Botanical Extraction
Plant materials undergo solvent extraction to separate berberine alkaloids from plant matrices.
3. Purification & Concentration
The crude extract is purified through filtration, concentration, and separation processes to remove unwanted plant compounds.
4. Hydrochloride Salt Formation
Purified berberine is reacted with hydrochloric acid to produce stable Berberine Hydrochloride.
5. Crystallization & Drying
The product undergoes controlled crystallization, drying, and milling to obtain uniform powder.
6. Quality Control Testing
Each batch is tested by HPLC and laboratory analysis to confirm:
- Berberine HCl assay
- Identity
- Purity
- Microbial safety
- Heavy metal compliance
Berberine HCl Powder in Supplements & Cosmetics Formula Solutions
Berberine HCl Powder is primarily used as a dietary supplement ingredient due to its botanical alkaloid properties. It is less common as a direct cosmetic active but can be incorporated into anti-aging, antioxidant, microbiome-support, and skin health formulations. Standard commercial supplement products commonly use 300–500 mg Berberine HCl per serving, with some formulas using divided daily doses.
1.Berberine HCl Powder for Supplements Capsules
| Ingredient | Amount | Function |
|---|---|---|
| Berberine HCl Powder (98%) | 500 mg | Primary active ingredient |
| Chromium Picolinate | 200 mcg | Mineral support for glucose metabolism |
| Cinnamon Extract 10:1 | 100 mg | Botanical metabolic support |
| Alpha Lipoic Acid | 50 mg | Antioxidant support |
| Rice Extract | q.s. | Capsule filler |
2.Berberine HCl Powder for Weight Management Supplements
| Ingredient | Amount |
|---|---|
| Berberine HCl 98% | 500 mg |
| Green Tea Extract EGCG 50% | 250 mg |
| Garcinia Cambogia Extract | 300 mg |
| L-Carnitine Tartrate | 500 mg |
| Chromium | 200 mcg |
3.Berberine HCl Powder for Functional Foods & Beverages
| Ingredient | Amount |
|---|---|
| Berberine HCl 98% | 300 mg |
| Inulin Fiber | 3 g |
| Resistant Starch | 2 g |
| Natural Lemon Flavor | 150 mg |
| Stevia | 50 mg |
We provide complete OEM solutions including formulation development, capsule filling, packaging, and finished supplement manufacturing.
Why Choose Peptidchem?
1. Free sample available
Berberine HCl Powder Suppliers 10-30g samples could be offered for your R&D trial. Qty: 1ton, Delivery method: FOB/CIF.
2. Quality and Purity
A Supplements Contract Manufacturer ensures that their Berberine Hydrochloride Extract is of the highest quality and purity. They often use third-party testing and provide a Certificate of Analysis (COA) to guarantee the product’s safety and efficacy.
3. Our Certificates
Over the years, we have been committed to product manufacture optimization and quality system establishment. We’ve set up the quality management system and obtained certificates for it. We provide ISO9001 , Halal, Kosher, etc.
4. Customized Bulk Supply
We support:
Small trial orders
Bulk container supply
Private label manufacturers
Ingredient distributors
5. Global Export Capability
Markets served:
USA
Europe
Australia
Canada
Middle East
Asia-Pacific
Peptidchem can supply bulk Berberine 98% HPLC Powder with customized active specifications, formulation support, COA documentation, and export-ready quality systems. Contact us today!
