At Peptidchem, a wholesale madecassoside powder bulk supplier. Product specification ≥95%, tested by HPLC. It is a white powder with good water solubility; a 1% aqueous solution is clear and transparent. It is commonly used in creams, serums, lotions, and masks targeting sensitive, dry, or aging skin. We provide comprehensive documentation COA, specification sheets, SDS, flowcharts, and other documents.
What is Madecassoside?
Madecassoside bulk powder is a highly purified bioactive compound derived from Centella Asiatica, a plant widely used in traditional medicine.
Madecassoside Powder is carefully extracted and purified to ensure consistent potency, high stability, and excellent compatibility in formulation systems. It is recognized for its anti-inflammatory, skin-soothing, and anti-aging properties, making it an essential ingredient in premium skincare ingredient for cosmetics.
Madecassoside Powder Specification
| Item |
Specification |
| Appearance |
White to off-white powder |
| Active Content (Madecassoside) |
≥95% |
| Assay Method |
HPLC |
| Loss on Drying |
≤ 1.0% |
| Residue on Ignition |
≤ 0.1% |
| Heavy Metals |
≤ 10 ppm |
| Arsenic (As) |
≤ 1 ppm |
| Lead (Pb) |
≤ 1 ppm |
| Cadmium (Cd) |
≤ 1 ppm |
| Mercury (Hg) |
≤ 0.1 ppm |
| Microbial Limit |
Total Plate Count ≤ 1000 CFU/g |
| |
Yeast & Mold ≤ 100 CFU/g |
| |
E. coli Negative |
| |
Salmonella Negative |
Madecassoside 98% Powder to Cosmetic Solutions & Applications
As a water-soluble triterpenoid saponin, Madecassoside 98% is ideal for creams, serums, lotions, and functional cosmetic products, supporting skin regeneration and barrier repair. Its high purity ensures consistent efficacy and stability in cosmetic formulations.
| Application |
Typical Dosage (% w/w) |
Formulation Notes |
Safety / Regulatory Specifications |
| Serum |
0.05 – 0.5% |
Dissolve in water or aqueous phase. Can be combined with hyaluronic acid, glycerin, or botanical extracts. Avoid high temperatures >60°C during mixing. |
pH: 5–7 |
| Irritation: Non-irritant in patch tests |
| Heavy Metals: Compliant with EU & US cosmetic regulations |
| Microbial Limit: TPC ≤ 1000 CFU/g, Yeast & Mold ≤ 100 CFU/g |
| Cream |
0.05 – 0.5% |
Add in cooled (<40°C) emulsified cream phase to prevent degradation. Compatible with oil-in-water (O/W) creams. |
Same as above |
| Lotion |
0.05 – 0.3% |
Water-based lotion, preferably added during the cooling phase. Ensure full dissolution for uniform distribution. |
Same as above |
| Face Mask (Powder / Gel Mask) |
0.1 – 0.5% |
Can be blended in dry powder masks or hydrated gel masks. Ensure complete dispersion to avoid clumping. |
Same as above |
| Eye Cream / Sensitive Skin Products |
0.05 – 0.2% |
Use lower concentration for delicate areas. Combine with soothing agents like panthenol or allantoin. |
Same as above |
*Notes for Formulators:
1.Solubility: Water-soluble; recommended to pre-dissolve in the aqueous phase.
2.Temperature Sensitivity: Avoid high heat during mixing; above 60°C may reduce activity.
3.Compatibility: Compatible with most cosmetic emulsifiers, humectants, and botanical actives.
4.Storage of Formulations: Finished products should be stored in cool, dry places, preferably <25°C, and protected from sunlight.
Why Choose Peptidchem?
Madecassoside 98% powder supplier by Peptidchem, is a dietary supplement and cosmetic peptides manufacturer with more than 20 years of experience. We have our own laboratories and warehouses in the United States. The company has obtained multiple certificationsISO9001, FDA, HALAL, KOSHER, FSSC22000, and thirteen patent certifications. Contact us now!
Cosmetic Manufacturer FAQs:
Q1: Is Madecassoside 98% Powder safe for cosmetic use?
A: Yes, Madecassoside is widely used in cosmetic formulations and has been evaluated for skin safety. Our batch testing ensures it is free from harmful contaminants.
Q2: Can this powder be used in oral supplements?
A: This product is primarily intended for cosmetic applications. Oral use requires separate safety and regulatory approvals.
Q3: What is the solubility of Madecassoside 98% Powder?
A: It is water-soluble and can be easily incorporated into aqueous cosmetic formulations.
Q4: Do you provide COA and MSDS?
A: Yes, all batches come with a Certificate of Analysis (COA) and Material Safety Data Sheet (MSDS) for export.
Q5: Can you provide OEM services?
A: Yes, we offer customized bulk packaging and formulation support for skincare manufacturers.
References
Shukla A, Rasik AM, Jain GK, et al. “Protective effect of Madecassoside against skin inflammation and oxidative stress.” Journal of Ethnopharmacology. 1999;68:15–19.
Kimura Y, Sumiyoshi M, et al. “Madecassoside promotes wound healing and collagen synthesis in human dermal fibroblasts.” Phytotherapy Research. 2001;15:150–153.
Chiang LC, Chiang W, et al. “Anti-inflammatory activity of Madecassoside from Centella asiatica.” Phytomedicine. 2005;12:559–565.
